At the Federal level, the National Response Framework is supported by the Response Federal Interagency Operational Plan (FIOP). The Response FIOP further defines the concepts, principles, structures, and actions introduced in the National Response Framework, with a focus on the Federal level.

The Response FIOP goes into more depth than the National Response Framework on how Federal agencies work together on Response and how they support or complement activities that take place in the private sector and at other levels of government.

The intent of the FIOP is to support local, state, tribal, territorial, insular-area, and Federal government plans to ensure a common operational focus.

Each mission area has their own FIOP that describes how the federal government aligns resources and delivers that mission's core capabilities. More information can be found at, https://www.fema.gov/federal-interagency-operational-plans