DOE provides the framework for a comprehensive and balanced National energy plan through the coordination and administration of the energy functions of the Federal government. Its primary responsibilities in the hazardous materials arena involve radioactive waste generated by the nuclear weapons program or by nuclear reactors, which supply energy.

DOE provides assistance in the removal and disposal of radioactive contamination, as well as in identifying the source and extent of radioactive releases. In addition, DOE conducts hazardous materials training workshops throughout the country.